Figure 4From: 1,25-Dihydroxyvitamin D3 increases the expression of the CaT1 epithelial calcium channel in the Caco-2 human intestinal cell lineEffect of 1,25-dihydroxyvitamin D Dose on CaT1 mRNA in Caco-2 cells. Cells were treated for 24 h with increasing doses (1–100 nM) of 1,25-dihydroxyvitamin D. The mean effect of 1,25-dihydroxyvitamin D (n= 3 studies) on CaT1 mRNA was evident at the lowest dose (10 -9 mol/L) investigated. In these experiments there was a further increase in expression at 10 -8 mol/L 1,25-dihydroxyvitamin D, but no further increase in expression at a 10-fold higher dose of 1,25-dihydroxyvitamin D.Back to article page