Figure 6

Spontaneous [Ca²⁺] _i variations in both undifferentiated and differentiated GL15 cells. Panels A, B and C show, respectively, a single [Ca²⁺]_i spike, low frequency [Ca²⁺]_i oscillations and high frequency [Ca²⁺]_i waves. 50% (n>200) of the cell population (differentiated or not) seemed to prime spontaneous intracellular Ca²⁺ movements. Time (s=seconds) is indicated on the abscissa; the ordinate gives the normalized fluorescence value (f/f₀).