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Table 1 Effect of high fat diet and adrenalectomy on serum hormones and pituitary POMC mRNA.

From: Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity

Group

n

Glucose (mg/dl)

Insulin (ng/ml)

Corticosterone (ng/ml)

Leptin (ng/ml)

Pituitary POMC (%)

Chow/Sham

8

135 ± 7

1.7 ± 0.3

86 ± 14

1.8 ± 0.5

100 ± 38.7

Chow/ADX

10

148 ± 5

1.4 ± 0.3

11 ± 5.3*

1.6 ± 0.2

228 ± 36*

Diet/Sham

8

127 ± 13

1.9 ± 0.5

117 ± 23

11 ± 2.5*

154 ± 40

Diet/ADX

11

144 ± 6

1.6 ± 0.2

31 ± 7.0†

8.0 ± 1.5*

329 ± 50†

  1. Effect of high fat diet and adrenalectomy on blood glucose (mg/dl), serum insulin (ng/ml), corticosterone (ng/ml), leptin peptide (ng/ml), and pituitary POMC mRNA (% chow sham-operated). Data are expressed as mean ± SEM. Groups with different symbols are statistically different (p < 0.05) by ANOVA followed by Tukey-Kramer post hoc test.
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BMC Physiology

ISSN: 1472-6793

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