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Figure 3 | BMC Physiology

Figure 3

From: 1,25-Dihydroxyvitamin D3 increases the expression of the CaT1 epithelial calcium channel in the Caco-2 human intestinal cell line

Figure 3

Early Temporal Response of CaT1 mRNA to 1,25-dihydroxyvitamin D in Caco-2 Cells. Caco-2 cells were treated with 1,25-dihydroxyvitamin D (10 -7 mol/L) for 0, 2, 4, 8 or 24 h. The bar graph illustrates the mean (SEM) fold-increase in CaT1 mRNA expression at each of the time points from 6 independent time course studies. There was a significant (p < 0.0001, ANOVA) time-dependent induction of CaT1 mRNA expression by 1,25-dihydroxyvitamin D with evidence of increased induction as early as 2 h and clear and progressive up regulation of CaT1 expression between 4 h and 24 h.

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BMC Physiology

ISSN: 1472-6793

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