Skip to main content

Table 1 Additional functional data, not included in Figure 1.

From: High calcium and dobutamine positive inotropy in the perfused mouse heart: myofilament calcium responsiveness, energetic economy, and effects of protein kinase C inhibition

Perfusate Ca2+ (mM):

Dias. P

Volume

Flow

Dry heart

Diastolic

 

(mmHg)

(μL)

(mL/min)

weight (g)

[Ca2+]i (nM)

1.5

3 ± 2

19.9 ± 0.8

2.2 ±0.1

0.029 ± 0.002

353 ± 60*

2.0

3 ± 3

23.3 ± 1.9

2.0 ± 0.3*

0.029 ± 0.002

375 ± 17†

2.5

5 ± 4

20.2 ± 0.6

2.3 ± 0.2†

0.025 ± 0.002

346 ± 93*

3.5

4 ± 4

20.4 ± 0.9

2.1 ± 0.2

0.025 ± 0.001

532 ± 53

3.5+Chelerythrine

2 ± 1

20.7 ± 1.6

2.2 ± 0.4

0.027 ± 0.001

369 ± 46*

Dobutamine

3 ± 3

23.3 ± 1.9

1.8 ± 0.2

0.029 ± 0.002

587 ± 41

  1. Symbols for coronary flow column: * p < 0.05 vs 2.5 mM; † p < 0.05 vs dobutamine Symbols for diastolic calcium column: * p < 0.005 vs perfusate calcium 3.5 mM and dobutamine; † p < 0.05 vs perfusate calcium 3.5 mM and dobutamine.