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Figure 5 | BMC Physiology

Figure 5

From: Functional analysis of a frame-shift mutant of the dihydropyridine receptor pore subunit (α1S) expressing two complementary protein fragments

Figure 5

EC coupling generated by two complementary fragments of α1S. Line scans (horizontal dimension is 2.05 seconds) of fluo-4 fluorescence show Ca2+ transients in response to the indicated 50-ms depolarization from a holding potential of -40 mV. Trace of integrated fluorescence in ΔF/Fo units is shown for each line scan. Each set of depolarizations is from a separate dysgenic myotube expressing the α1S construct(s) indicated at the top of each column. A 16-color calibration bar in ΔF/Fo units is included in Fig. 3 for visual reference.

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