Figure 1
From: Endothelial [Ca2+]i is an integrating signal for the vascular tone in rat aortae
Mounting of the aortic en face preparation for simultaneous measurements of EC [Ca2+]i and vascular displacement (a). Movement of EC images in response to PE (b). The arrows point to an arbitrarily selected endothelial calcium image that shifts upward during vascular contraction in response to cumulative concentrations of PE. Bar equals 100 μm. Effects of PE on the EC [Ca2+]i and contraction of aortic en face preparation (c). PE causes vasoconstriction (○) without alteration of EC [Ca2+]i (●) (n = 5)