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Table 1 Effects of phenylephrine and calcium-free Krebs-Ringer buffer on EC [Ca2+]i and corresponding vasoconstriction.

From: Endothelial [Ca2+]i is an integrating signal for the vascular tone in rat aortae

  Basal PE (5 × 10-8 mol/L)
   Normal Ca2+-free
EC [Ca2+]i (nmol/L)    
   - inhibitors 92.4+10.4 85.6+15.5 51.4+5.1*
   + inhibitors 80.0+15.2 83.8+9.9 53.5+10.3*
Contraction (%)    
   - inhibitors 0 100 211.0+29.9*
   + inhibitors 0 100 103.3+1.6*#
  1. Results were taken from experiments similar to the one shown in Fig 4. Data are expressed as mean ± SE (n = 5). - inhibitors: without pretreatment of endothelial autacoid inhibitors + inhibitors: pretreatment with all endothelial autacoid inhibitors * P < 0.05 (Ca2+-free vs. normal buffer) # P < 0.05 (with inhibitors vs. no inhibitors)