Skip to main content
Figure 2 | BMC Physiology

Figure 2

From: Increased expression and local accumulation of the Prion Protein, Alzheimer Aβ peptides, superoxide dismutase 1, and Nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetes

Figure 2

ELISA assays measuring increased levels of Alzheimer Aβ peptides in diabetic muscle. Levels of Alzheimer Aβ peptides ending at amino acid 40 (x-40) or 42 (x-42) were determined in total muscle proteins from three diabetic and three normal control rabbits. ~7.5-fold increases were measured for Aβ40 and Aβ42 peptides in diabetic muscle compared to normal control muscle (P < 0.0005 and P < 0.0025, respectively). Graphs show pg/ml of Aβ detected in muscle samples determined using standard peptide controls (Covance). Graphs show mean values of 3 diabetic and 3 control animals with standard deviations.

Back to article page

BMC Physiology

ISSN: 1472-6793

Contact us