Table 2 Enriched biological processes showing dysregulation in zebrafish and mammalian obesity
From: Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity
| Zebrafish | Rat | Mouse | Human | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Process | NES | MC | p-value | NES | MC | p-value | NES | MC | p-value | NES | MC | p-value |
| Blood coagulation | 2.3 | 3.1 | 0.0E+0 | 2.0 | 1.1 | 0.0E+0 | 1.7 | 1.1 | 9.5E-3 | 1.8 | 1.5 | 0.0E+0 |
| Platelet activation | 2.0 | 4.8 | 0.0E+0 | 1.8 | 1.1 | 6.1E-3 | 1.7 | 1.0 | 1.9E-2 | |||
| Fatty acid metabolism | 2.2 | 1.6 | 0.0E+0 | 1.8 | 1.0 | 0.0E+0 | 1.8 | 1.0 | 4.5E-3 | |||
| Cholesterol efflux | 1.6 | 1.1 | 0.0E+0 | 1.9 | 1.4 | 5.7E-3 | 1.8 | 1.3 | 0.0E+0 | |||
| Triglyceride metabolism | 1.8 | 2.0 | 0.0E+0 | 1.8 | 1.2 | 5.8E-3 | 1.7 | 1.1 | 9.5E-3 | |||