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Table 2 Enriched biological processes showing dysregulation in zebrafish and mammalian obesity

From: Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity

  Zebrafish   Rat    Mouse   Human  
Process NES MC p-value NES MC p-value NES MC p-value NES MC p-value
Blood coagulation 2.3 3.1 0.0E+0 2.0 1.1 0.0E+0 1.7 1.1 9.5E-3 1.8 1.5 0.0E+0
Platelet activation 2.0 4.8 0.0E+0 1.8 1.1 6.1E-3 1.7 1.0 1.9E-2    
Fatty acid metabolism 2.2 1.6 0.0E+0 1.8 1.0 0.0E+0 1.8 1.0 4.5E-3    
Cholesterol efflux 1.6 1.1 0.0E+0 1.9 1.4 5.7E-3 1.8 1.3 0.0E+0    
Triglyceride metabolism 1.8 2.0 0.0E+0 1.8 1.2 5.8E-3 1.7 1.1 9.5E-3    
  1. NES: normalized enrichment score; MC: median change in gene expression in the gene set