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Table 1 Changes of different genes expression before marathon and after marathon.

From: RETRACTED ARTICLE: The effect of marathon on mRNA expression of anti-apoptotic and pro-apoptotic proteins and sirtuins family in male recreational long-distance runners

 

Before marathon

After marathon

Mean difference

95% CI Lower - Upper

Magnitude of the difference

 

Mean ± SD

Mean ± SD

  

Effect size

Interpretation

bax

3.35 ± 0.91

0.60 ± 0.21

-2.75*

-3.43 to -2.07

0.90

large

bcl-2

0.91 ± 0.21

3.25 ± 1.17

2.34*

1.56 to 3.12

0.83

large

Cu-Zn SOD

0.69 ± 0.25

3.50 ± 0.74

2.81*

2.25 to 3.37

0.93

large

HSP70

1.27 ± 0.53

3.65 ± 1.31

2.38*

1.73 to 3.02

0.88

large

iNOS

0.95 ± 0.08

4.10 ± 0.66

3.15*

2.67 to 3.63

0.96

large

Mn-SOD

0.52 ± 0.30

5.20 ± 1.11

4.68*

3.73 to 5.63

0.93

large

SIRT1

1.12 ± 0.28

3.60 ± 0.69

2.48*

1.90 to 3.06

0.91

large

SIRT3

0.97 ± 0.26

0.18 ± 0.11

-0.79*

-0.98 to -0.59

0.90

large

SIRT4

1.11 ± 0.25

0.20 ± 0.13

-0.91*

-1.14 to -0.68

0.90

large

Ratio bax: bcl-2

2.10 ± 0.19

0.87 ± 0.27

-1.23*

-1.43 to -1.03

0.96

large

  1. * = Significant difference between before and after marathon (P < 0.0001); 95% CI = 95% confidence intervals of the difference