Figure 2
From: Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps
Hyperglycemic (HG) clamp in anesthetized HFD-fed GhrR KO and WT mice. The HG clamps were performed over a 90 min period as previously described [29], with the exception of modifications described in the methods section. The hyperglycemic target was 300 mg/dl. Changes in plasma insulin concentration during HG clamp: first phase (A) and second phase (B); glucose infusion rate (C). Data are the means ± SE n = 8-10/group. *p < 0.05 vs. WT mice.