Figure 12
From: VEGF signaling mediates bladder neuroplasticity and inflammation in response to BCG
Representative photomicrographs of double immunofluorescence (CD31 and KI67) of the urinary bladder mucosa isolated from mice instilled chronically (4 weekly instillations) of: BCG, VEGF 165 , and VEGF 121 . The area of CD31+ blood vessels was used to calculated microvessel density (Figure 13A) and the co-localization between CD31+ endothelial cells and KI67 expression was used to calculate the degree of angiogenesis (Figure 13 B).