Figure 4

Summary whole-cell patch clamp currents and reversal voltage with only Na⁺ or Li⁺ as the major permeant ions. A) Bar graph of the reversal voltage (left panel), the currents at -100 mV (middle panel) and the conductance at -100 mV (right panel) in Na⁺-rich symmetrical solutions (B2, P2) and Li⁺-rich bath and Na⁺-rich pipette solutions (B4, P2). Data were taken from the rapid transition between Na⁺-rich and Li⁺-rich bath (time points 3 and 4' in Fig 3A) in order to minimize the contribution of rundown. B) Summary of current-voltage (I-V) relationships of the whole cell currents in symmetrical Na⁺-rich solutions (B2, P2) and Li⁺-rich bath and Na⁺-rich pipette solutions (B4, P2) at steady state (near 200 ms).