Figure 3

Temporal expression of JAK/STAT during myogenic differentiation in human muscle cells. Representative Western blots of protein extracted from near confluent primary human myoblasts that were induced to differentiate during the specified times. Phosphorylation of JAK2 (Tyr1007/1008) and STAT3 (Tyr705) increases during differentiation, while JAK1 (Tyr1022/1023) and STAT1 (Tyr701) were only apparent during proliferation.