Figure 3
Effect of conditional c-myc deletion on liver growth following starvation. Male and female mice were fed ad libitum (control), fasted for 48 hr (fasted), or fasted for 48 hr then refed ad libitum for 24 hr (refed). A. The graph shows liver:carcass weight ratios for c-myc+/+ (open bars) and c-mycfl/fl (closed bars) Alb-Cre expressing mice expressed as the mean + 1 SD. n ≥ 3 mice/group. B. Liver homogenates were prepared and protein concentration determined using the bichoninic acid method. Total liver protein was then calculated based on total liver weight. The graph shows total liver protein content for c-myc+/+ (open bars) and c-mycfl/fl (closed bars) Alb-Cre expressing mice expressed as the mean + 1 SD. n ≥ 3 mice/group.