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Table 2 Function of genes potentially involved in the ion transfer for supplying eggshell mineral precursors in hen uterus

From: Identification of uterine ion transporters for mineralisation precursors of the avian eggshell

Name Gene symbol Functional data Transfer type
Transient receptor potential cation channel subfamily V member 6 TRPV6   Ca2+ channel (plasma membrane)
Calbindin 28 K CALB1 [11, 14, 28] Ca2+ intracellular transporter (intracellular)
Endoplasmic reticulum calcium ATPase 1 ATP2A1   Ca2+ ATPases (endoplasmic & plasma membrane)
Endoplasmic reticulum calcium ATPase 2 ATP2A2   
Endoplasmic reticulum calcium ATPase 3) ATP2A3   
IP3 receptor1 ITPR1   Ca2+ channels (endoplasmic membrane)
IP3 receptor2 ITPR2   
IP3 receptor3 ITPR3   
Ryanodine receptor 1 RYR1   Ca2+ channel (endoplasmic membrane)
Plasma membrane calcium-transporting ATPase 1 (PMCA1) ATP2B1   Ca2+/H+ exchanger (plasma membrane)
Plasma membrane calcium-transporting ATPase 2 (PMCA2) ATP2B2   
Plasma membrane calcium-transporting ATPase 4 (PMCA4) ATP2B4 [16]  
Sodium/calcium exchanger 1 SLC8A1   Na+/Ca2+ exchanger (plasma membrane)
Sodium/calcium exchanger 3 SLC8A3   
Amiloride-sensitive sodium channel subunit alpha SCNN1A [31] Na+ channels (plasma membrane)
Amiloride-sensitive sodium channel subunit beta SCNN1B [31]  
Amiloride-sensitive sodium channel subunit gamma SCNN1G [31]  
Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 [18] Na+/K+ exchanger (plasma membrane)
Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1 [18]  
Solute carrier family 4 member 4 SLC4A4   Na+/HCO3- co-transporters (plasma membrane)
Solute carrier family 4 member 5 SLC4A5   
Solute carrier family 4 member 7 SLC4A7   
Solute carrier family 4 member 10 SLC4A10   
Inward rectifier potassium channel 2 KCNJ2   Inward rectifiers K+ channels (plasma membrane)
Inward rectifier potassium channel 5 KCNJ15   
Inward rectifier potassium channel 16 KCNJ16   
Calcium-activated potassium channel subunit alpha-1 KCNMA1   K+ channel (plasma membrane)
Carbonic anhydrase 2 CA2 [6] Catalyse HCO3- formation (plasma membrane)
Carbonic anhydrase 4 CA4   
Carbonic anhydrase 7 CA7   
Solute carrier family 4 member 8 SLC4A8   HCO3-/Cl- exchangers (plasma membrane)
Solute carrier family 4 member 9 SLC4A9   
Solute carrier family 26 member 9 SLC26A9   
Vacuolar H ATPase B subunit osteoclast isozyme ATP6V1B2   H+ pump (organelles and plasma membrane
Cystic fibrosis transmembrane conductance regulator CFTR   Cl- channel (plasma membrane)
Chloride channel protein 2 CLCN2   Cl- channel (plasma membrane)
H(+)/Cl(−) exchange transporter 5 CLCN5   Cl-/H+ exchanger (plasma membrane)