Table 2 Function of genes potentially involved in the ion transfer for supplying eggshell mineral precursors in hen uterus
From: Identification of uterine ion transporters for mineralisation precursors of the avian eggshell
Name | Gene symbol | Functional data | Transfer type |
|---|---|---|---|
Transient receptor potential cation channel subfamily V member 6 | TRPV6 | Â | Ca2+ channel (plasma membrane) |
Calbindin 28 K | CALB1 | Ca2+ intracellular transporter (intracellular) | |
Endoplasmic reticulum calcium ATPase 1 | ATP2A1 | Â | Ca2+ ATPases (endoplasmic & plasma membrane) |
Endoplasmic reticulum calcium ATPase 2 | ATP2A2 | Â | Â |
Endoplasmic reticulum calcium ATPase 3) | ATP2A3 | Â | Â |
IP3 receptor1 | ITPR1 | Â | Ca2+ channels (endoplasmic membrane) |
IP3 receptor2 | ITPR2 | Â | Â |
IP3 receptor3 | ITPR3 | Â | Â |
Ryanodine receptor 1 | RYR1 | Â | Ca2+ channel (endoplasmic membrane) |
Plasma membrane calcium-transporting ATPase 1 (PMCA1) | ATP2B1 | Â | Ca2+/H+ exchanger (plasma membrane) |
Plasma membrane calcium-transporting ATPase 2 (PMCA2) | ATP2B2 | Â | Â |
Plasma membrane calcium-transporting ATPase 4 (PMCA4) | ATP2B4 | [16] | Â |
Sodium/calcium exchanger 1 | SLC8A1 | Â | Na+/Ca2+ exchanger (plasma membrane) |
Sodium/calcium exchanger 3 | SLC8A3 | Â | Â |
Amiloride-sensitive sodium channel subunit alpha | SCNN1A | [31] | Na+ channels (plasma membrane) |
Amiloride-sensitive sodium channel subunit beta | SCNN1B | [31] | Â |
Amiloride-sensitive sodium channel subunit gamma | SCNN1G | [31] | Â |
Sodium/potassium-transporting ATPase subunit alpha-1 | ATP1A1 | [18] | Na+/K+ exchanger (plasma membrane) |
Sodium/potassium-transporting ATPase subunit beta-1 | ATP1B1 | [18] | Â |
Solute carrier family 4 member 4 | SLC4A4 | Â | Na+/HCO3- co-transporters (plasma membrane) |
Solute carrier family 4 member 5 | SLC4A5 | Â | Â |
Solute carrier family 4 member 7 | SLC4A7 | Â | Â |
Solute carrier family 4 member 10 | SLC4A10 | Â | Â |
Inward rectifier potassium channel 2 | KCNJ2 | Â | Inward rectifiers K+ channels (plasma membrane) |
Inward rectifier potassium channel 5 | KCNJ15 | Â | Â |
Inward rectifier potassium channel 16 | KCNJ16 | Â | Â |
Calcium-activated potassium channel subunit alpha-1 | KCNMA1 | Â | K+ channel (plasma membrane) |
Carbonic anhydrase 2 | CA2 | [6] | Catalyse HCO3- formation (plasma membrane) |
Carbonic anhydrase 4 | CA4 | Â | Â |
Carbonic anhydrase 7 | CA7 | Â | Â |
Solute carrier family 4 member 8 | SLC4A8 | Â | HCO3-/Cl- exchangers (plasma membrane) |
Solute carrier family 4 member 9 | SLC4A9 | Â | Â |
Solute carrier family 26 member 9 | SLC26A9 | Â | Â |
Vacuolar H ATPase B subunit osteoclast isozyme | ATP6V1B2 | Â | H+ pump (organelles and plasma membrane |
Cystic fibrosis transmembrane conductance regulator | CFTR | Â | Cl- channel (plasma membrane) |
Chloride channel protein 2 | CLCN2 | Â | Cl- channel (plasma membrane) |
H(+)/Cl(−) exchange transporter 5 | CLCN5 |  | Cl-/H+ exchanger (plasma membrane) |