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Figure 2 | BMC Physiology

Figure 2

From: The ΔF508-CFTR mutation inhibits wild-type CFTR processing and function when co-expressed in human airway epithelia and in mouse nasal mucosa

Figure 2

Confirming the specificity of the dominant negative-like effect of ΔF-CFTR on WT-CFTR in native IB3-1 CF bronchial epithelial cells. A. Similar co-expression biochemical experiments with G551D-CFTR and WT-CFTR. B. Increasing amounts of ΔF-CFTR do not affect the maturation and processing of a different glycosylated membrane protein, the purinergic receptor channel, P2X4.

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BMC Physiology

ISSN: 1472-6793

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