Table 1 Body weight and body composition, physical activity and meal patterns of wild type (WT), Sox2-Cre:Errβ+/lox, and Sox2-Cre:Errβlox/lox mice
From: Estrogen-related receptor β deficiency alters body composition and response to restraint stress
Genotype | Age | Body composition | Meal patterns | |||||
|---|---|---|---|---|---|---|---|---|
Body weight | Fat mass | Lean mass | Activity | Pellets | Satiety ratio | IMI | ||
(grams) | (grams) | (grams) | (beam breaks) | (number) | (IMI/meal size) | (minutes) | ||
WT | 3 weeks | 13.1 ± 0.5 | 2.09 ± 0.09 | 10.06 ± 0.41 | ||||
Sox2-Cre:Errβ+/lox | 3 weeks | 14.0 ± 0.7 | 2.58 ± 0.16* | 10.56 ± 0.62* | ||||
Sox2-Cre:Errβlox/lox | 3 weeks | 12.9 ± 0.8 | 1.64 ± 0.17 | 10.51 ± 0.61 | ||||
WT | 9 months | 36.5 ± 0.9 | 12.19 ± 0.65 | 23.09 ± 0.46 | 67207 ± 8601 | 128 ± 15 | 8.3 ± 0.9 | 107 ± 17 |
Sox2-Cre:Errβ+/lox | 9 months | 46.1 ± 3.0* | 21.43 ± 1.84* | 24.00 ± 0.63 | 93599 ± 9879 | 238 ± 35* 5.6 ± 0.7# | 102 ± 10 | |
Sox2-Cre:Errβlox/lox | 9 months | 28.4 ± 1.3* | 5.69 ± 0.74* | 21.64 ± 0.40* | 133741 ± 20533* | 260 ± 57* | 4.1 ± 0.7* | 67 ± 11* |