Table 2 Summary of phenotype difference between Sox2-Cre:Errβ+/lox, Sox2-Cre:Errβlox/lox and Nes2-Cre:Errβlox/lox mice, relative to wild type (WT)
From: Estrogen-related receptor β deficiency alters body composition and response to restraint stress
Phenotype | Sox2- Cre:Errβ+/lox | Sox2- Cre:Errβlox/lox | Nes2- Cre:Errβlox/lox | |
|---|---|---|---|---|
Body Composition | ||||
Body weight | ↑, | ↓, | ↑ | |
Fat mass | ↑, | ↓, | NC | |
Lean mass | ↓, | ↓, | ↑ | |
Hormone and Neuropeptides | ||||
Corticosterone | ↑, | ↓, | NA | |
Corticosterone (DY131) | ↑, | ↓, | NA | |
Crh expression | ↑, | ↑, | ↓ | |
Crh expression (DY131) | ↑↑, | ↑↑, | NA | |
Npy expression | ↑, | ↑, | ↓ | |
Agrp expression | ↑, | ↑, | NA | |
Stress Behavior | ||||
Acoustic startle response | NA, | NA, | ↑ | |
Meal patterns | ||||
Total pellets consumed | ↑, | ↑, | NC | |
Inter Meal interval (IMI) | NC, | ↓, | ↓ | |
Satiety Ratio | ↓#, | ↓, | ↓ | |