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Table 1 Kinetic values for taurocholic acid transport by wild-type and polar-residue mutant mouse Slc10a2 proteins

From: Importance of uncharged polar residues and proline in the proximal two-thirds (Pro107–Ser128) of the highly conserved region of mouse ileal Na+-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression

 

Km(μM)

Vmax(pmol·mg protein–1·min–1)

Wild type

24.0 (2.0)

1620 (50)

T110A

20.2 (2.3)

4010 (170)

Y117F

20.7 (4.1)

806 (61)

S128A

42.0 (3.7)

7930 (340)

  1. Data are expressed as mean (standard error).