Freely fed | Starved | Refed | Within groups p<0.05 | Among groups p<0.05 | |||
---|---|---|---|---|---|---|---|
μmol/liter | |||||||
Essential AA | |||||||
Isoleucine | wt | 61 ± 6 | 56 ± 4 | 67 ± 9 | ns | ||
IGF- | 59 ± 6 | 72 ± 7 | 50 ± 6 | ns | ns | ||
Leucine | wt | 124 ± 17 | 84 ± 6 | 179 ± 29 | 0.05 | ||
IGF- | 111 ± 12 | 114 ± 11 | 131 ± 20 | ns | ns | ||
Valine | wt | 161 ± 16 | 120 ± 6 | 176 ± 20 | ns | ||
IGF- | 152 ± 12 | 156 ± 13 | 143 ± 17 | ns | ns | ||
BCAA | wt | 346 ± 38 | 260 ± 16 | 422 ± 58 | 0.05 | ||
IGF- | 321 ± 28 | 342 ± 31 | 325 ± 43 | ns | ns | ||
Lysine | wt | 258 ± 16 | 246 ± 16 | 277 ± 14 | ns | ||
IGF- | 281 ± 21 | 282 ± 26 | 273 ± 21 | ns | ns | ||
Methionine | wt | 55 ± 7 | 41 ± 5 | 97 ± 10 | 0.001 | ||
IGF- | 48 ± 5 | 38 ± 3 | 77 ± 13 | 0.01 | ns | ||
Phenylalanine | wt | 287 ± 37 | 389 ± 107 | 386 ± 93 | ns | ||
IGF- | 402 ± 86 | 277 ± 36 | 311 ± 72 | ns | ns | ||
Threonine | wt | 147 ± 14 | 119 ± 10 | 207 ± 13 | 0.05 | ||
IGF- | 125 ± 7 | 114 ± 8 | 162 ± 20 | 0.05 | 0.05 | ||
Tryptophan | wt | 34 ± 4 | 30 ± 3 | 42 ± 4 | ns | ||
IGF- | 36 ± 3 | 35 ± 4 | 33 ± 3 | ns | ns | ||
Essential AA | wt | 1127 ± 80 | 1086 ± 119 | 1433 ± 89 | 0.05 | ||
IGF- | 1213 ± 112 | 1089 ± 70 | 1181 ± 91 | ns | ns | ||
Non-essential AA | |||||||
Alanine | wt | 337 ± 33 | 262 ± 37 | 547 ± 47 | 0.001 | ||
IGF- | 283 ± 26 | 194 ± 13 | 459 ± 44 | 0.001 | 0,01 | ||
Arginine | wt | 77 ± 12 | 20 ± 7 | 43 ± 10 | 0.01 | ||
IGF- | 56 ± 14 | 41 ± 9 | 30 ± 10 | ns | ns | ||
Aspartic acid | wt | 37 ± 6 | 34 ± 3 | 25 ± 3 | ns | ||
IGF- | 22 ± 2 | 40 ± 6 | 33 ± 4 | ns | ns | ||
Asparagine | wt | 31 ± 2 | 27 ± 2 | 41 ± 2 | 0.01 | ||
IGF- | 25 ± 2 | 25 ± 1 | 32 ± 3 | ns | 0.01 | ||
Citrulline | wt | 30 ± 3 | 20 ± 2 | 34 ± 2 | 0.01 | ||
IGF- | 29 ± 2 | 20 ± 1 | 30 ± 3 | 0.01 | ns | ||
Glutamic acid | wt | 166 ± 18 | 152 ± 16 | 129 ± 15 | ns | ||
IGF- | 166 ± 11 | 138 ± 13 | 158 ± 23 | ns | ns | ||
Glutamine | wt | 538 ± 36 | 520 ± 30 | 578 ± 31 | ns | ||
IGF- | 553 ± 27 | 516 ± 42 | 560 ± 35 | ns | ns | ||
Glycine | wt | 174 ± 18 | 170 ± 17 | 178 ± 10 | ns | ||
IGF- | 150 ± 9 | 140 ± 15 | 175 ± 24 | ns | ns | ||
Histidine | wt | 53 ± 4 | 50 ± 3 | 70 ± 4 | 0.01 | ||
IGF- | 57 ± 4 | 52 ± 4 | 64 ± 4 | ns | ns | ||
Serine | wt | 108 ± 12 | 85 ± 5 | 136 ± 5 | 0.01 | ||
IGF- | 93 ± 16 | 75 ± 5 | 118 ± 9 | 0.01 | ns | ||
Tyrosine | wt | 330 ± 23 | 395 ± 65 | 339 ± 82 | ns | ||
IGF- | 323 ± 39 | 239 ± 40 | 285 ± 59 | ns | ns | ||
Ornitine | wt | 88 ± 22 | 90 ± 12 | 109 ± 16 | ns | ||
IGF- | 109 ± 16 | 83 ± 15 | 115 ± 10 | ns | ns | ||
α-Aba | wt | 7 ± 1 | 8 ± 1 | 9 ± 1 | ns | ||
IGF- | 6 ± 1 | 6 ± 1 | 8 ± 1 | ns | ns | ||
Non-ess. AA | wt | 1977 ± 142 | 1835 ± 149 | 2237 ± 89 | ns | ||
IGF- | 1872 ± 71 | 1570 ± 112 | 2065 ± 125 | 0.05 | ns | ||
Total AA | wt | 3103 ± 219 | 2921 ± 264 | 3669 ± 143 | 0.05 | ||
IGF- | 3085 ± 171 | 2659 ± 180 | 3246 ± 205 | 0.08 | ns |