Figure 4From: Significance of KATP channels, L-type Ca2+ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles In vivoEffects of consecutive application of 1 μM cromakalim and increasing concentrations of glibenclamide. A. Effects of consecutive application of 1 μM cromakalim and 10 μM glibenclamide on arteriolar responses during high and low oxygen tensions were evaluated (*p < 0.05 vs. high oxygen, †p < 0.05 vs. control, 1 μM crom and wash-out during low oxygen, ‡p < 0.05 vs. papaverine, n = 5). B. Effects of consecutive application of 1 μM cromakalim and 100 μM glibenclamide on arteriolar responses during high and low oxygen tensions were evaluated (*p < 0.05 vs. high oxygen, †p < 0.05 vs. control, 1 μM crom and wash-out during low oxygen, ‡p < 0.05 vs. papaverine, n = 5).Back to article page