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Table 1 Drug uptake with the drinking water (mg/kg/d) in renovascular-hypertension models: 2-kidney-1-clip, 1-kidney-1-clip

From: Sympathoactivation and rho-kinase-dependent baroreflex function in experimental renovascular hypertension with reduced kidney mass

 

2-kidneys-1-clip model of hypertension

1-kidney-1-clip model of hypertension

P

Rho-kinase inhibitor SAR407899A

10.5 ± 2.4

10.9 ± 3.5

ns

Irbesartan

26.8 ± 2.0

NA

NA

  1. Statistical analysis was performed between groups.