Figure 1

Protocol for Study 1 to investigate the efficacy of preconditioning via α₁-adrenoceptors or adenosine (A) receptors alone and in combination with IP (n = 6 specimens/group): (i) time-matched aerobic control, (ii) SI/R alone, (iii) IP induced with 5 min of SI/ 5 min R before SI, (iv) phenylephrine (P) for 5 min and 5 min washout (W) before SI, (v) adenosine (A) for 5 min and 5 min washout (W) before SI, (vi) phenylephrine (P) for 5 min and 5 min washout (W) before IP, (vii) adenosine (A) for 5 min and 5 min washout (W) before IP and (viii) adenosine (A) for 5 min and 5 min washout (W) followed by phenylephrine (P) for 5 min and 5 min washout (W) prior to SI.