Figure 6

Creatine Kinase (CK) leakage into the media (A) during the 120 min reoxygenation period and MTT reduction by the slices (B) at the end of the reoxygenation period in human atrial myocardium subjected to various protocols (see Figure 3) to investigate the sequence of activation of the mediators of pharmacological and ischemic preconditioning (Study 3). Data are expressed as mean ± SEM of six experiments. ^*p < 0.05 vs SI/R alone group. (CHE: chelerythrine, 5-HD: 5-hydroxydecanoate, SB: SB203580, PMA: phorbol-12-myristate-13-acetate).