Table 2 Glomerular filtration rate (GFR) in wild type and in heterozygous and homozygous COMT gene deleted mice in the control group and in the group subjected to isotonic sodium loading. C2 is at t = 60 min, just before the start of isotonic sodium loading, and E4 is at t = 180 min just before the end of the experiment.
From: Reduced natriuretic response to acute sodium loading in COMT Gene deleted mice
C2 | E4 | |
|---|---|---|
GFR (mlSmin -1 ·g -1 kw) CONTROL GROUP | ||
Wild type | 0.78±0.08 | 0.85±0.11 |
Heterozygous | 0.87±0.13 | 0.70±0.06 |
Homozygous | 0.84±0.21 | 0.85±0.12 |
GFR (ml·min -1 ·g -1 kw) SODIUM LOADING | ||
Wild type | 0.85±0.09 | 0.91±0.12 |
Heterozygous | 0.84±0.07 | 1.16±0.05 |
Homozygous | 0.85±0.10 | 0.76±0.06 |