Figure 7
From: Blockade of maitotoxin-induced oncotic cell death reveals zeiosis
BAECs rescued from MTX-induced lytic cell death have elevated caspase-3 activity. BAECs were treated with 0.3 nM MTX for 2.5 min at which time the action of MTX was stopped by addition of 5 μM U73343. Cells were harvested after 48 hr and specific caspase-3 activity was determined using the fluorescence substrate assay (M/U). For control, caspase-3 activity was determined in cells treated with U73343 alone (IU) or vehicle (DMSO). Values represent the mean ± se (n = 3) relative to no-treatment controls.