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Figure 3 | BMC Physiology

Figure 3

From: Heat induced HSP20 phosphorylation without increased cyclic nucleotide levels in swine carotid media

Figure 3

Dependence of contractile force on ser16-HSP20 and putative PKC-HSP20 phosphorylation in tissues maximally stimulated with histamine. Upper panel: Mean data demonstrate the relation between ser16-HSP20 phosphorylation (mol Pi at ser 16 / mol HSP20) and contractile stress for all tissues presented in Figs. 1 and 2. All tissues were stimulated with 10 μM histamine for 10 min. The tissues treated for 4 hours at 47.5°C are shown as an open symbol and is not included in the linear regression. All other tissues are shown as filled circles. Overall there was a good inverse correlation between ser16-HSP20 phosphorylation and contractile force with these heat pretreatment protocols (r2 = 0.90, solid line is regression line, dotted line are 95% confidence intervals). Lower panel. Mean data demonstrate the relation between putative PKC-HSP20 phosphorylation (mol Pi at the PKC site / mol HSP20) and contractile stress. There was little relation between putative PKC-HSP20 phosphorylation and contractile force with these heat pretreatment protocols.

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