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Figure 2 | BMC Physiology

Figure 2

From: Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression

Figure 2

Effects of fasting on hypothalamic gene expression in intact and fasted mice. (A) Hypothalamic AGRP is induced by fasting in intact mice however the fasting associated induction is blocked by adrenalectomy. (B) Fasting reduces hypothalamic POMC mRNA in intact mice but not in adrenalectomized mice. (C) Similar to AGRP, hypothalamic NPY mRNA is induced in intact mice but not in adrenalectomized mice. Data are expressed as mean ± SEM. Groups with different letters are statistically different (p < 0.05), reflecting ANOVA followed by Tukey-Kramer post hoc tests comparing every group to every other group. Thus groups with the same letter do not differ from each other at a p < 0.05 level.

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