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Figure 4 | BMC Physiology

Figure 4

From: Monitoring immediate-early gene expression through firefly luciferase imaging of HRS/J hairless mice

Figure 4

Common gene expression patterns in anesthetized and overdosed mice. (A) Adult CMV::luc mouse imaged while under pentobarbital anesthesia lasting one to four hours. Expression was not obviously different from mice given an overdose. Expression shown as an overlay on a reference image. (B) Mice recovered within an hour and produced circadian rhythms in wheel running activity in constant darkness. Corresponding phase of previous light/dark cycle shown below. The rhythms in wheel-running activity were typical of mice maintained in darkness with a period less than 24 hours. Open boxes: when mouse was out of cage for imaging. Arrows: one daily activity onset. The data was double-plotted (48 hours across) so that circadian rhythms can be easily followed.

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