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Table 3 Clearance of 125I-labeled LPL from blood and uptake in liverin the presence and absence of heparin

From: Effects of heparin on the uptake of lipoprotein lipase in rat liver

Time after injection (min)

% of injected 125 I-labeled LPL

 

No heparin

Heparin

 

Blood

Liver

Liver

Active LPL

   

2

 

32.6 ± 3.1

13.9 ± 0.6

15

8.5 ± 13.6

51.5 ± 2.8

30.4 ± 1.4

60

6.7 ± 5.5

18.2 ± 1.7

22.8 ± 0.4

Inactive LPL

   

15

9.4 ± 0.7

50.0 ± 5.5

 

60

6.2 ± 1.0

18.8 ± 3.1

 
  1. Rats were injected with active or inactive 125I-labeled LPL either directly, or five min after intravenous injection of heparin. After the indicated times the rats were killed, blood samples were taken from the heart and livers were removed. The values have been corrected for the contribution of blood remaining in the liver, and are means ± SEM, n = 5.