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Table 1 Mean (± SE) ionized calcium levels before (pre) and after (post) injection in wild type and Casr+/- mice. P values apply to the comparison of respective post versus pre values, and to the post values versus the corresponding post-saline value.

From: Physiological studies in heterozygous calcium sensing receptor (CaSR) gene-ablated mice confirm that the CaSR regulates calcitonin release in vivo

Genotype Injection Pre Post p value
Wild type Saline (16) 1.28 ± 0.03 1.26 ± 0.02 -
Wild type 500 μmol/kg (13) 1.29 ± 0.02 1.34 ± 0.04 < 0.01
Wild type 5 mmol/kg (8) 1.29 ± 0.02 1.55 ± 0.06 < 0.01
Casr +/- Saline (20) 1.42 ± 0.02 1.34 ± 0.04 -
Casr +/- 500 μmol/kg (25) 1.42 ± 0.02 1.50 ± 0.02 < 0.01
Casr +/- 5 mmol/kg (23) 1.40 ± 0.01 1.71 ± 0.03 < 0.01