Table 2 CK leakage during the first 2 hours of reoxygenation and MTT reduction at the end of the reoxygenation period of right atrial muscles (n = 6/group) after 90 minutes of simulated ischaemia/reoxygenation (SI/R) in the presence and absence of the caspase-3 inhibitor z.DEVD.FMK (70 nM).
Group | MTT | P value | CK | P value |
|---|---|---|---|---|
Aerobic Control | 290.3 ± 32.3 | 2.5 ± 0.2 | ||
Aerobic Control plus C3i | 298.0 ± 30.4 | NS | 2.7 ± 0.1 | NS |
SI/R | 212.7 ± 23.1 | 5.4 ± 0.4 | ||
SI/R plus C3i | 220.3 ± 18.4 | NS | 5.7 ± 0.5 | NS |