Figure 2

Heart rate (HR) in hypophysectomized (Hx, solid line), growth hormone supplemented Hx (GH, solid squares) and in intact rats (solid triangles). The first two days (-4 to -2) represent non-supplemented basal measurements of HR in all groups. At day -2, all Hx rats received thyroxine and glucocorticoid [T4+GC] treatment with mini-osmotic pumps, whereas the intact rats underwent sham operation. At day zero, the onset of GH treatment (mini-osmotic pumps implantation) was performed in the GH animals, whereas both intact and Hx animals underwent sham operation. * indicate p<0.05 between pre- and post-GH treatment in GH group.