Figure 7From: Troglitazone, a PPAR-γ activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-αTNF-α induced phosphorylation of NF-kB p65 is prevented by troglitazone, a PPAR-γ ligand. TNF-α (1 ng/ml, 1 h) induced phosphorylation of NF-kB p65 was significantly attenuated by the PPAR-γ ligand, troglitazone (20 μM). Alone, troglitazone also attenuated phosphorylation of NF-kB p65.Back to article page