Skip to main content
Figure 1 | BMC Physiology

Figure 1

From: Streptozotocin-induced diabetes in the rat is associated with changes in vaginal hemodynamics, morphology and biochemical markers

Figure 1

Effect of diabetes on vaginal blood flow in rats. Female Sprague-Dawley rats, at 8–10 weeks of age, were fasted for 18–24 h and administered 0.02 M citrate saline buffer (Control) or streptozotocin (65 mg/kg) in citrate buffer (Diabetic) by intraperitoneal injection. After 8 weeks, rats were anesthetized and the vaginal blood flow response to pelvic nerve stimulation was recorded by laser Doppler flowmetry. The pelvic nerve was stimulated for 30 seconds at 5, 10, and 20 Hz. Shown are representative real time recordings of vaginal blood flow (black) expressed as tissue perfusion units (TPU; left axis) and systemic arterial pressure (gray) expressed as millimeters of Hg (right axis).

Back to article page