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Table 4 Soft tissue composition and body weight

From: An extensive phenotypic characterization of the hTNFα transgenic mice

Parameter

Genotype

Females

Males

  

RC

RC

HFD

Tissue area

WT

22.99 ± 0.30 (n = 7)

27.34 ± 0.59 (n = 8)

31.70 ± 0.67 (n = 8)

 

TG

21.96 ± 0.51 (n = 5)

24.66 ± 0.33**(n = 7)

24.87 ± 0.49*** (n = 5)

Total tissue mass

WT

22.18 ± 0.57

32.00 ± 1.22

40.46 ± 1.48

 

TG

20.92 ± 0.69

26.09 ± 0.53**

26.63 ± 0.97***

Fat mass

WT

2.47 ± 0.22

6.37 ± 0.8

15.33 ± 1.05

 

TG

1.97 ± 0.12

3.20 ± 0.26**

5.45 ± 0.68***

Lean mass

WT

19.71 ± 0.36

25.63 ± 0.59

25.13 ± 0.47

 

TG

18.95 ± 0.57

22.89 ± 0.35**

21.81 ± 0.35***

% fat

WT

11.15 ± 0.72

19.53 ± 1.67

37.57 ± 1.37

 

TG

9.39 ± 0.28

12.20 ± 0.82**

20.08 ± 1.91***

% lean

WT

88.85 ± 0.72

80.47 ± 1.67

62.43 ± 1.37

 

TG

90.61 ± 0.28

87.80 ± 0.82**

79.92 ± 1.91***

Body weight

WT

24.16 ± 1.02

32.19 ± 1.15

40.17 ± 1.46

 

TG

22.01 ± 0.75

26.46 ± 0.50**

26.72 ± 0.91***

  1. Values represent the mean ± SEM. RC is regular chow and HFD is high fat diet. The level of significance is shown by asterisks: * P < 0.05, ** 0.001 <P < 0.01, *** P < 0.001.