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Table 1 Failure location of the bone-ligament-bone complex at 3 weeks post-injury.

From: Systemic administration of IGF-I enhances healing in collagenous extracellular matrices: evaluation of loaded and unloaded ligaments

Failure Location Scar Region Tibial Third of the Ligament Tibial Avulsion
Sham Control N/A 6 0
Amb + Saline 6 0 0
Amb + GH 6 0 0
Amb + IGF 5 1 0
Amb + GH + IGF 6 0 0
HU + Saline 5 0 1
HU+ GH 6 0 0
HU + IGF 5 0 1
HU+ GH + IGF 6 0 0
  1. The strong majority (>96%) of tissues failed in the ligament and not by avulsion, indicating that the measured mechanical changes are due to changes in the ligament properties and not bone.