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Figure 4 | BMC Physiology

Figure 4

From: Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms

Figure 4

Measurement of the number of [top panel] PCNA- and [lower panel] CK-19-positive cholangiocytes in liver sections (5 μm, 3 slides analyzed per group) and [c] PCNA protein expression in purified female cholangiocytes from NaCl- or prolactin-treated rats. Administration of prolactin to normal female rats increased the number of PCNA-positive cholangiocytes (arrows) and CK-19-positive cholangiocytes compared with normal rats treated with NaCl. Orig. magn., ×20 (PCNA) and ×10 (CK-19). Data are mean ± SEM of 5 values obtained from the 3 slides evaluated per each group of animal. * p < 0.05 vs. the corresponding value of NaCl-treated rats.

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