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Table 1 Serum biochemical parameters.

From: The level of hypotension during hemorrhagic shock is a major determinant of the post-resuscitation systemic inflammatory response: an experimental study

 

Group sham

Group shock-40

Group shock-30

 

AST (Mean ± SD, U/L)

Baseline

18.0 ± 1.9

25.0 ± 9.7a

21.7 ± 9.3c, e

End of shock

20.4 ± 2.2

25.4 ± 8.9a

29.3 ± 7.2c, e

30 min

20.8 ± 3.1

29.0 ± 8.4a

37.0 ± 5.0c, e

60 min

24.0 ± 1.6

32.6 ± 9.1a

44.0 ± 2.6c, f

90 min

23.4 ± 3.2

39.0 ± 13.9b

54.7 ± 6.0d, e

120 min

24.6 ± 2.7

45.8 ± 15.4b

61.0 ± 6.6d, f

 

ALT (Mean ± SD, U/L)

Baseline

17.6 ± 3.2

20.2 ± 7.4a

17.7 ± 4.2c, e

End of shock

19.6 ± 3.6

23.4 ± 7.5a

20.3 ± 8.5c, e

30 min

18.4 ± 2.5

25.0 ± 7.2a

23.0 ± 8.5c, e

60 min

18.8 ± 2.6

28.4 ± 8.3a

24.3 ± 8.1c, e

90 min

18.2 ± 1.6

31.0 ± 8.9a

24.6 ± 8.1c, e

120 min

19.4 ± 1.5

34.4 ± 8.5b

31.7 ± 8.1c, e

 

Creatinine (Mean ± SD, mg/dl)

Baseline

1.10 ± 0.42

0.90 ± 0.07a

1.10 ± 0.20c, e

End of shock

1.08 ± 0.38

0.96 ± 0.15a

1.33 ± 0.32c, e

30 min

1.04 ± 0.34

1.02 ± 0.08a

1.27 ± 0.40c, e

60 min

0.94 ± 0.21

1.08 ± 0.13a

1.37 ± 0.35c, e

90 min

0.88 ± 0.28

1.08 ± 0.22a

1.50 ± 0.36d, e

120 min

0.90 ± 0.29

1.22 ± 0.32a

1.63 ± 0.46d, f

  1. Serum concentrations of aspartate aminotransferase (AST), alanine aminotransferase (AST) and creatinine of animals undergoing sham operation (group sham); animals undergoing hemorrhagic shock to MAP 40 mmHg (group shock-40) before start of resuscitation; and animals undergoing hemorrhagic shock to MAP 30 mmHg (group shock-30) before start of resuscitation.
  2. Statistical comparisons after Bonferroni correction
  3. Group sham vs group shock-40: apNS (non-significant); bp < 0.05
  4. Group sham vs group shock-30: cpNS (non-significant); dp < 0.05
  5. Group shock-40 vs group shock-30: epNS (non-significant); fp < 0.05