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Table 2 Serum oxidative parameters and endotoxin.

From: The level of hypotension during hemorrhagic shock is a major determinant of the post-resuscitation systemic inflammatory response: an experimental study

 

Group sham

Group shock-40

Group shock-30

 

MDA (Mean ± SD, μmol/mL)

Baseline

0.61 ± 0.16

0.81 ± 0.15a

0.69 ± 0.07c, e

End of shock

0.88 ± 0.09

1.77 ± 0.09b

1.69 ± 0.04d, e

30 min

1.04 ± 0.27

2.32 ± 0.12b

2.16 ± 0.08d, e

60 min

1.14 ± 0.34

2.61 ± 0.19b

2.65 ± 0.06d, e

90 min

1.26 ± 0.40

2.85 ± 0.22b

2.79 ± 0.67d, e

120 min

1.36 ± 0.49

3.23 ± 0.19b

3.20 ± 0.09d, e

 

TAS (Mean ± SD, μmol/L)

Baseline

0.59 ± 0.11

0.47 ± 0.14a

0.39 ± 0.08c, e

End of shock

0.70 ± 0.12

0.80 ± 0.19a

0.75 ± 0.13c, e

30 min

0.73 ± 0.11

0.86 ± 0.18a

0.77 ± 0.09c, e

60 min

0.77 ± 0.10

0.75 ± 0.16a

0.61 ± 0.13c, e

90 min

0.79 ± 0.11

0.59 ± 0.08b

0.55 ± 0.10d, e

120 min

0.77 ± 0.08

0.49 ± 0.01b

0.47 ± 0.08d, e

 

LPS (Median-range, EU/mL)

Baseline

0.26 (0.05–0.56)

0.39 (0.05–4.18)a

0.05 (0.05–1.38)c, e

End of shock

0.10 (0.05–0.13)

0.57 (0.13–1.65)b

0.05 (0.05–0.85)c, e

30 min

0.05 (0.05–0.17)

0.32 (0.05–0.56)a

0.05 (0.05–0.96)c, e

60 min

0.05 (0.05–0.48)

0.24 (0.06–0.49)a

0.14 (0.05–0.89)c, e

90 min

0.05 (0.05–0.54)

0.60 (0.05–1.23)a

0.05 (0.05–1.45)c, e

120 min

0.05 (0.05–0.46)

0.42 (0.05–1.58)a

0.05 (0.05–8.38)c, e

  1. Serum concentrations of malndialdehyde (MDA), total antioxidant status (TAS) and endotoxin (LPS) of animals undergoing sham operation (group sham); animals undergoing hemorrhagic shock to MAP 40 mmHg (group shock-40); and animals undergoing hemorrhagic shock to MAP 30 mmHg (group shock-30).
  2. Statistical comparisons after Bonferroni correction
  3. Group sham vs group shock-40: apNS (non-significant); bp < 0.05
  4. Group sham vs group shock-30: cpNS (non-significant); dp < 0.05
  5. Group shock-40 vs group shock-30: epNS (non-significant); fp < 0.05