Comparison of morphometric parameters between pups 42 days old. Variation in adult weight and size observed in the offspring of a population of mice subjected to ISF or control diet is shown. (a) indicates the general trend of decreased size (P = 0.03, *) and weight (P = 0.06, #) in the ISF group with regard to controls, when pooling males and females. Size differences in (a) are explained by variations in both sexes, as shown in (b). Weight differences in (a) are accounted for by variations only in males, which are heavier in the control group than in the ISF group (P = 0.04, ‡), as can be seen in (c). Also, in the control group males are heavier that females (P < 0.001; c, right, ±), difference that is suppressed in the ISF group (P = 0.3; c, left).