Figure 4
From: Functional and pharmacological characterization of a Shal-related K+ channel subunit in Zebrafish
Effects of NCS-1 on zShal3 currents. A and B: Representative traces of zShal3 currents expressed with or without NCS-1.C: Averaged current-voltage (I-V) relationship of peak zShal3 current with (●) or without (○) NCS-1. The inset depicts the conductance-voltage curves that were constructed by dividing the current by the driving force and normalizing to the maximal conductance (Gmax) at +100 mV.D: zShal3 and zShal3/NCS-1 currents, normalized to the maximal peak amplitudes at +50 mV, to illustrate the effects of NCS-1 on the inactivation time course.E: Voltage dependence of steady-state inactivation for zShal3 (○) and zShal3/NCS-1 currents (●)(n = 8 for each experiment).F: Time course of the recovery from inactivation for zShal3 (○) and zShal3/NCS-1 currents (●)(n = 8 for each experiment).