Figure 7

GC7 prevents actions of casein, amino acids and polyamines. Survivorship curves were determined in the absence (magenta) or the presence of 10 mM GC7 (blue) or of 10 mM DAH (dotted line in panels D and H). Percentage changes in longevity by GC7 or DAH are indicated for each dietary condition. A log rank test was used to compare survivorship curves. **: p < 0.0001, *: p < 0.001, no asterisk: p > 0.001. Dietary conditions were: A, starvation, B, 10% sucrose diet, C, 10% sucrose diet supplemented with 0.05% casein, D-F, 10% sucrose diet supplemented with 10 mM amino acids or polyamines as indicated. Sample sizes were: A (50 each), B (control, 237; GC7, 99), C (control, 79; GC7, 86), D (control, 179; GC7, 135; DAH, 40), E (control 108; GC7, 103) and F (control, 130; GC7, 193), G (control, 208; GC7, 80), H (control, 208; GC7, 80), I (control, 162; GC7, 89; DAH, 40) and J (control, 110; GC7, 50).