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Table 1 SmCavβ modulates inactivation of Cav2.3 currents

From: Atypical properties of a conventional calcium channel β subunit from the platyhelminth Schistosoma mansoni

 

Cav2.3 alone

Cav2.3 + SmCavβ

Steady state inactivation

  

   V50 (mV)

-8 ± 4 (3)

-49 ± 3 (3)*

   Slope (mV/e-fold)

12 ± 2 (3)

10 ± 1 (3)

Macroscopic inactivation

  

   τfast (ms)

16 ± 3 (9)

31 ± 5 (7)*

   % Contribution

66 ± 2%

55 ± 5%*

   τslow (ms)

69 ± 13 (9)

116 ± 20 (7)

   % Contribution

34 ± 2%

45 ± 5%*

Recovery from inactivation

  

   τrec-80 mV (ms)

178 ± 28 (3)

252 ± 17 (4)

   τrec-100 mV (ms)

71 ± 7 (3)

168 ± 16 (3)*

   τrec-120 mV (ms)

38 ± 1 (3)

109 ± 10 (3)*

  1. Data represent mean ± s.e.m. Number of repeats is indicated in parentheses. Asterisks indicate statistically significant difference (Student t test, P < 0.05).