Figure 2
VGF-deficient mice on a C57Bl6 background have decreased fat and lean body mass, and decreased bone mineral density and content. Body weight (Panel A) (grams), body composition (Panels B and C) [lean mass (LM) and fat mass (FM)] (grams), length (Panel D) (cm), bone mineral density (BMD) (Panel E) (g/cm2) and bone mineral content (BMC) (Panel F) (grams), were determined in VGFR mice using dual emission x-ray absorption. Data are expressed as mean ± SEM (n = 7-8 male mice of each genotype per group).