Figure 5

Effect of α/β CaMKII co-overexpression on mitochondrial gene expression. A) Bar graph visualising the mean + SE of assessed mitochondrial proteins in control-transfected (light grey filled bar) and α/β CaMKII-transfected (dark grey filled bar) SOL muscle (n = 6). Representative examples of detected mitochondrial protein are shown below. *, p ≤0.05 vs. control-transfected (Wilcoxon Test). B) Bar graph of mean + SE of the differences in expression of selected gene transcripts between α/β CaMKII-transfected and control-transfected SOL muscle (n = 6). * denotes p ≤0.05 vs. control-transfected muscle (T-test). C) Microscopic images visualising the association of the mitochondrial marker, COXIV, with transfected (Tf) and non-transfected (NTf) fibres in α/β CaMKII-transfected GM and SOL muscle. D) Bar graph showing the mean + SE of COXIV levels in transfected (n = 54 for GM and n = 38 for SOL) and non-transfected (n = 51 for GM and n = 35 for SOL) muscle fibres. The corresponding p-values are indicated.