| |
SOL
|
GM
|
|---|
|
Non-transfected
|
Control-transfected
|
α/βCaMKII-transfected
|
Non-transfected
|
Control-transfected
|
α/βCaMKII-transfected
|
|---|
|
Ftwitch (mN)
|
216±9.3
|
178 ±15a
|
174 ±20
|
2548 ±86
|
2377 ±175a
|
2380 ±178
|
|
Fmax (mN)
|
1083±57
|
555 ±57a
|
568 ±80
|
8864 ±395
|
7594 ±638a
|
8078 ±723
|
|
Fatigue (%)
|
10.5 ±3.6
|
18.8 ±5.3
|
22.7 ±5.4
|
67.5 ±2.1
|
65.3 ±2.9
|
67.6 ±2.2
|
|
TTP (ms)
|
105 ±14
|
133 ±7.9a
|
108 ±7.3b
|
43.0 ±3.3
|
50.9 ±4.0a
|
44.2 ±2.4b
|
|
HRT (ms)
|
121 ±18
|
168 ±4.6a
|
142 ±6.9b
|
42.9 ±5.9
|
54.0 ±6.0a
|
46.2 ±3.9b
|
- Data are shown as mean ± SE. For abbreviations see Figure 2. Fatigue: % decrease in force after the 50 maximal tetanic contractions of the high-intensity exercise, relative to first contraction; a: Main effect of electro-transfer procedure (p<0.05); b: Main effect of α/βCaMKII overexpression (p<0.05).
