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Table 1 Effect of α/βCaMKII-transfection vs. controls on contractile parameters

From: CaMKII content affects contractile, but not mitochondrial, characteristics in regenerating skeletal muscle

 

SOL

GM

Non-transfected

Control-transfected

α/βCaMKII-transfected

Non-transfected

Control-transfected

α/βCaMKII-transfected

Ftwitch (mN)

216±9.3

178 ±15a

174 ±20

2548 ±86

2377 ±175a

2380 ±178

Fmax (mN)

1083±57

555 ±57a

568 ±80

8864 ±395

7594 ±638a

8078 ±723

Fatigue (%)

10.5 ±3.6

18.8 ±5.3

22.7 ±5.4

67.5 ±2.1

65.3 ±2.9

67.6 ±2.2

TTP (ms)

105 ±14

133 ±7.9a

108 ±7.3b

43.0 ±3.3

50.9 ±4.0a

44.2 ±2.4b

HRT (ms)

121 ±18

168 ±4.6a

142 ±6.9b

42.9 ±5.9

54.0 ±6.0a

46.2 ±3.9b

  1. Data are shown as mean ± SE. For abbreviations see Figure 2. Fatigue: % decrease in force after the 50 maximal tetanic contractions of the high-intensity exercise, relative to first contraction; a: Main effect of electro-transfer procedure (p<0.05); b: Main effect of α/βCaMKII overexpression (p<0.05).