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Fig. 5 | BMC Physiology

Fig. 5

From: The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion

Fig. 5

Effects of inhibition of gastric H+,K+-ATPase on H+- and K+-fluxes from stria vascularis. a Summary traces (N = 7) of effect on H+ flux of perfusion of SCH28080 (10 nM). Box shows the duration of the experimental period. b Concentration-response curve (N = 3–7) for stimulation of strial H+-flux by SCH28080. Data fit by the Michaelis-Menton equation. c Small inhibition of K+ flux from stria vascularis by SCH28080 (10 nM; N = 7)) and absence of effect (SCH, SCH28080) after inhibition of K+ flux by bumetanide (200 μM; N = 6; bumet). *, P < 0.05; ns, not significant

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